{"id":3358,"date":"2025-11-01T15:14:09","date_gmt":"2025-11-01T13:14:09","guid":{"rendered":"https:\/\/vythoulkas.ro\/clasificarea-embrionilor\/"},"modified":"2025-12-01T17:01:12","modified_gmt":"2025-12-01T15:01:12","slug":"embryo-grading","status":"publish","type":"post","link":"https:\/\/vythoulkas.ro\/en\/embryo-grading\/","title":{"rendered":"Embryo Grading"},"content":{"rendered":"\n<p>Assisted reproductive technologies offer couples who cannot conceive naturally an important chance at parenthood. However, completing a fertility treatment successfully can be a physically and emotionally demanding journey.<\/p>\n\n\n\n<p>Embryo quality is one of the key milestones along this journey. Understanding how embryos are graded can make the process easier and even encouraging.<\/p>\n\n\n\n<section class=\"quote-component full bg-tutu-400 py-[40px] overflow-hidden\">\n    <div class=\"section-container mx-auto px-4\">\n        <div class=\"lg:grid flex flex-col lg:grid-rows-4 grid-cols-6 lg:gap-x-[12px] items-start\">\n\n            <div class=\"col-start-1 col-end-7 lg:col-end-5 row-start-1 row-end-3 lg:row-end-3 flex flex-col lg:block\">\n                                    <h2 class=\"inline font-light m-0 align-bottom\">\n                        \u201cYou deserve to be heard, seen, treated with respect, and supported throughout your life.\u201d                    <\/h2>\n                \n                            <\/div>\n\n            <div class=\"grid self-stretch grid-cols-6 grid-rows-4 h-full lg:contents\">\n                                    <div class=\"lg:max-w-full max-w-[410px] -mb-[20px] lg:m-0 col-start-4 lg:col-start-5 col-end-7 row-start-1 row-end-3 lg:row-start-1 lg:row-end-4 self-stretch overflow-hidden\">\n                        <img decoding=\"async\" src=\"https:\/\/vythoulkas.ro\/wp-content\/uploads\/2025\/10\/Doctor-Patient-Care.jpg\" alt=\"Ilustra\u021bie cu Dr. Andreas Vythoulkas oferind sprijin \u0219i \u00eengrijire personalizat\u0103 unei paciente \u00een cadrul tratamentelor FIV.\" class=\"w-full h-full object-cover\">\n                    <\/div>\n                \n                                    <div class=\"max-h-[min(50vw,300px)] lg:max-h-[462px] col-start-1 col-end-6 row-start-3 row-end-5 lg:col-start-2 lg:col-end-5 lg:row-start-3 lg:row-end-5 self-stretch overflow-hidden\">\n                        <img decoding=\"async\" src=\"https:\/\/vythoulkas.ro\/wp-content\/uploads\/2025\/10\/Expecting-Mother.jpg\" alt=\"Ilustra\u021bie cu o femeie \u00eens\u0103rcinat\u0103 reprezent\u00e2nd succesul tratamentelor de fertilitate oferite de Dr. Andreas Vythoulkas.\" class=\"w-full h-full object-cover\">\n                    <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/section>\n\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>If You Have Day 3 Embryos<\/strong><\/h2>\n\n\n\n<p>After egg retrieval and laboratory fertilization, day 3 is the first major evaluation point for your embryos. In some cases, a day-3 transfer is performed at this stage.<\/p>\n\n\n\n<p>What exactly are day-3 embryos? At this stage, the cells divide but do not grow in size, remaining roughly the size of an unfertilized egg. On day 3, the embryologist examines the embryo\u2019s morphology under a high-power microscope, focusing primarily on the number and appearance of the cells.<\/p>\n\n\n\n<p>An embryo developing normally ideally has between 6 and 10 cells, with 8 being optimal. Research shows that day-3 embryos with 8 or more cells have notably higher live-birth rates.<\/p>\n\n\n\n<p>However, not all good-quality embryos follow the rules. Some may have 3, 5, or 6 cells because cell division is not always synchronized.<\/p>\n\n\n\n<p>While counting the cells is straightforward, evaluating their appearance is more difficult, especially if the embryo cannot be viewed straight on. Day-3 embryos are graded from 1 to 4 (or 5), depending on lab protocol, with grade 1 being the highest.<\/p>\n\n\n\n<p>What does the embryologist look for?<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Each cell should have a nucleus<\/li>\n\n\n\n<li>Cells should be similar in size<\/li>\n\n\n\n<li>Fragmentation: up to 20% is acceptable; higher levels may compromise cell function due to cytoplasm loss<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>If You Have Day 5 Embryos<\/strong><\/h2>\n\n\n\n<p>Some fertility clinics prefer transferring embryos on day 5, when they reach about 80 cells and are known as blastocysts. At this stage, the embryologist can better evaluate two key structures:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>The inner cell mass (ICM)<\/strong>\u00a0\u2014 which forms the fetus<\/li>\n\n\n\n<li><strong>The trophectoderm<\/strong>\u00a0\u2014 which forms the placenta; a normal trophectoderm is essential for ongoing development<\/li>\n<\/ul>\n\n\n\n<p>Blastocyst grading is complex and typically combines a number grade (1\u20136) with letters (A, B, or C), where A indicates the highest quality. Importantly, these grades can change from one day to the next. A blastocyst graded C may later progress to an A, and blastocoel expansion may move from grade 1 to 6 within 24 hours.<\/p>\n\n\n\n<p>Studies show that higher-graded blastocysts are associated with better pregnancy and live-birth outcomes, while lower-graded ones show lower rates \u2014 but not in all cases. Grading cannot predict success with certainty, and hope should never be lost based solely on these scores. \u00eens\u0103 nu \u00eentotdeauna. Notele nu pot prezice cu certitudine succesul unei sarcini, iar speran\u021ba trebuie men\u021binut\u0103 indiferent de scorul ob\u021binut.<\/p>\n\n\n\n<section class=\"talk-to-expert-component my-[80px] lg:my-[120px]\">\n    <div class=\"section-container mx-auto bg-baby-blue-100 max-w-[1116px]\">\n        <div class=\"grid grid-cols-1 lg:grid-cols-2 items-stretch gap-[40px]\">\n\n            <!-- Left Column: Text Content -->\n            <div class=\"flex flex-col justify-start items-start gap-[40px] px-[18px] lg:pl-[40px] pt-[40px] lg:pb-[20px] lg:pr-0\">\n                                    <span class=\"font-[450] m-0 body-md\">Contact me<\/span>\n                \n                                    <h4 class=\"font-normal m-0\">\n                        Talk with me about                                                    <br><strong class=\"font-bold bg-baby-blue-300\" >Embryo Grading<\/strong>\n                                            <\/h4>\n                \n                                    <div class=\"m-0 body-md wysiwyg-content\">\n                        If you have questions related to embryo grading or would like recommendations on evaluating and monitoring your newborn during the first days of life, you may request an individual consultation at any time. A thorough assessment helps determine the most suitable monitoring and support plan for your child.                    <\/div>\n                \n                                    <div class=\"align-self-end\">\n                        \n<a href=\"https:\/\/vythoulkas.ro\/en\/contact\/\"\n   target=\"_self\"\n   class=\"group inline-flex items-center gap-2 h-14 py-2 rounded-full border-[1px] transition-colors duration-300 hover:no-underline border-baby-blue-800 hover:border-baby-blue-500 text-baby-blue-800 hover:text-baby-blue-800 pl-6 pr-2\">\n\n    <span class=\"font-[400] text-base whitespace-nowrap\">Talk with me now<\/span>\n            <span class=\"flex items-center justify-center w-10 h-10 duration-300 transition-transform rounded-full bg-baby-blue-800 text-baby-blue-100 -rotate-45 group-hover:rotate-0\">\n             <svg class=\"w-6 h-6 text-baby-blue-100\" fill=\"none\" stroke=\"currentColor\" viewBox=\"0 0 24 24\"\n                  xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                  <path stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\"2\" d=\"M14 5l7 7m0 0l-7 7m7-7H3\"><\/path>\n             <\/svg>\n        <\/span>\n    <\/a>\n                    <\/div>\n                            <\/div>\n\n            <!-- Right Column: Image -->\n            <div class=\"items-stretch flex\">\n                <div class=\"relative w-full h-full overflow-hidden\">\n                                            <img decoding=\"async\" class=\"lg:inset-0 lg:absolute w-full h-full max-h-full block object-cover\" src=\"https:\/\/vythoulkas.ro\/wp-content\/uploads\/2025\/10\/Program-National-FIV-2025.-Etape-Eligibilitate-Costuri.jpg\" alt=\"Program Na\u021bional FIV 2025 | Etape, Eligibilitate &amp; Costuri\">\n                                    <\/div>\n            <\/div>\n\n        <\/div>\n    <\/div>\n<\/section>\n<style>\n    @media screen and (max-width: 992px) {\n        .talk-to-expert-component {\n            padding-left: 0;\n            padding-right: 0;\n        }\n        \/*.expert-subtitle {\n            color: var(--text-body, #262B2F);\n            leading-trim: both;\n            text-edge: cap;\n            font-kerning: none;\n\n            !* Body\/Body Medium Mobile *!\n            font-family: var(--type-font-family-secondary);\n            font-size: var(--font-size-body-sm, 16px);\n            font-style: normal;\n            font-weight: 450;\n            line-height: var(--line-height-body-sm, 24px); !* 150% *!\n        }*\/\n    }\n<\/style>\n","protected":false},"excerpt":{"rendered":"<p>Clasificarea embrionilor explic\u0103 evolu\u021bia lor \u00een ziua 3 \u0219i ziua 5. Afl\u0103 ce \u00eenseamn\u0103 scorurile \u0219i cum influen\u021beaz\u0103 \u0219ansele de ob\u021binere a unei sarcini.<\/p>\n","protected":false},"author":3,"featured_media":2392,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7],"tags":[],"post_author":[],"class_list":["post-3358","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles"],"acf":[],"_links":{"self":[{"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/posts\/3358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/comments?post=3358"}],"version-history":[{"count":2,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/posts\/3358\/revisions"}],"predecessor-version":[{"id":3381,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/posts\/3358\/revisions\/3381"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/media\/2392"}],"wp:attachment":[{"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/media?parent=3358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/categories?post=3358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/tags?post=3358"},{"taxonomy":"post_author","embeddable":true,"href":"https:\/\/vythoulkas.ro\/en\/wp-json\/wp\/v2\/post_author?post=3358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}